The Myers’ Cocktail IV: What It Is, What It Does, and What Research Suggests

The Myers’ Cocktail is one of the most recognized nutrient IV formulations used in integrative and functional medicine.

While it has gained popularity in wellness settings, its origin and proposed mechanisms are rooted in clinical nutrient therapy.

At Tailored to You Medical Aesthetics in Mitchell, South Dakota, we believe patients should understand what is being infused, why it’s used, and what current research suggests.

What Is the Myers’ Cocktail?

The original Myers’ Cocktail was developed by Dr. John Myers in the 1960s. It is a combination of intravenous vitamins and minerals typically including:

• Magnesium chloride

• Calcium gluconate

• Vitamin C (ascorbic acid)

• B-complex vitamins

• Vitamin B12

Exact concentrations may vary depending on provider protocol and patient needs.

The goal is direct intravenous delivery of micronutrients to bypass gastrointestinal absorption and achieve higher serum concentrations than oral supplementation alone.

What Does It Actively Do in the Body?

The nutrients within a Myers’ Cocktail serve specific physiological roles:

Magnesium

• Supports neuromuscular function

• Assists in ATP production

• Involved in over 300 enzymatic reactions

• Plays a role in inflammation regulation

Vitamin C

• Potent antioxidant

• Supports immune cell function

• Involved in collagen synthesis

• Assists in oxidative stress reduction

B Vitamins

• Support mitochondrial energy production

• Assist in nervous system regulation

• Aid in red blood cell formation

• Contribute to methylation pathways

When delivered intravenously, these nutrients may temporarily elevate plasma levels beyond what oral intake can achieve.

What Does Research Say?

Research on Myers’ Cocktail specifically is limited and evolving. However, smaller clinical studies and observational data have explored its use in conditions such as:

• Chronic fatigue

• Fibromyalgia

• Migraines

• Asthma

• Muscle spasm disorders

A small study published in the Journal of Alternative and Complementary Medicine suggested symptom improvement in fibromyalgia patients receiving IV nutrient therapy. However, larger randomized controlled trials are still needed.

Much of the scientific discussion centers around:

• Magnesium’s role in neuromuscular regulation

• Vitamin C’s antioxidant capacity

• B-vitamin support of mitochondrial dysfunction

It is important to note that IV nutrient therapy is considered complementary care — not a replacement for primary medical treatment.

What About Autoimmune Conditions?

Autoimmune conditions involve dysregulation of the immune system and chronic inflammation. Some emerging research suggests that:

• Oxidative stress may contribute to autoimmune activity

• Micronutrient deficiencies may worsen immune imbalance

• Magnesium and vitamin C may influence inflammatory pathways

That said, Myers’ Cocktail is not a treatment or cure for autoimmune disease.

Some patients with autoimmune conditions report improvements in energy levels, recovery, or symptom burden when nutrient deficiencies are addressed. However, this should always be coordinated with a patient’s primary or specialty provider.

At Tailored to You, IV therapy is offered as supportive care, not disease management.

Who Might Benefit?

Patients commonly seek Myers’ Cocktail IV for:

• General fatigue

• High stress states

• Athletic recovery

• Frequent illness

• Travel recovery

• Suspected nutrient depletion

Before infusion, we review medical history, medications, kidney function considerations, and contraindications to ensure safety.

Safety and Clinical Oversight

IV nutrient therapy should be administered under medical supervision.

At Tailored to You, infusions are:

• Delivered by licensed nursing staff

• Overseen by a Nurse Practitioner

• Prepared using regulated ingredients

• Administered in a monitored setting

Screening is performed prior to infusion, and dosing is individualized when appropriate.

The Bottom Line

The Myers’ Cocktail IV is not magic.
It is not a cure.
It is not a replacement for comprehensive medical care.

It is a targeted nutrient infusion designed to support cellular function, mitochondrial energy production, and immune balance in appropriate candidates.

If you are considering IV therapy, a consultation is always recommended first. Proper screening ensures safety, appropriate dosing, and alignment with your overall health plan.

Other IV options available at Tailored to You include:

• Immunity IV

• Tri-Immune

• The Hangover

• Glutathione

Each formulation is designed with a specific purpose and is administered under medical supervision.

As always, education comes before infusion.